department of pharmacology


Primary Faculty

Krzysztof Palczewski


Krzysztof Palczewski, Ph.D.
Professor and Department Chair
Phone: (216) 368-4497 Fax: (216) 368-1300
Email: kxp65@case.edu
W319 Wood Building
Research: Mapping the Visual Transduction System.
Laboratory


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Anthony Berdis, Ph.D.
Assistant Professor
Phone: (216) 368-4723 Fax: (216) 368-3395
Email: anthony.berdis@case.edu
W341 Wood Building
Research: Mechanistic studies of the enzymes and protein complexes involved in DNA replication and DNA methylation.
Laboratory


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Chris Dealwis, Ph.D.
Associate Professor
Phone: (216) 368-1652, 368-3337 Fax: (216) 368-1300
Email: chris.dealwis@case.edu
W303A Wood Buldiing
Research: To study the structure-function relationship of macromolecules using structural biology and biochemical tools.


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Diane Dowd, Ph.D.
Assistant Professor
Phone: (216) 368-4076 Fax: (216) 368-3395
Email: diane.dowd@case.edu
W309B Wood Building
Research: Mechanisms of Ca2+-induced gene expression.


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Andreas Engel, Ph.D.
Professor
Phone: (216) 368-0411 Fax: (216) 368-1300
Email: Andreas.Engel@case.edu
RT300 Research Towers
Research: Research concerns the structure and function of membrane proteins of different origin. A major effort is invested in the study of aquaglyceroporins. Electron crystallography and atomic force microscopy are used to analyze two-dimensional crystals assembled from membrane proteins and lipids


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John Feng, Ph.D.
Assistant Professor
Phone: (216) 368-3751 Fax: (216) 368-1300
Email: john.feng@case.edu
W309A Wood Building
Research: Dissecting the genetic mechanisms of dopamine neurotransmission-related human diseases
Laboratory


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Hisashi Fujioka, Ph.D.
Associate Professor
Director of the CWRU SOM EM Facility
Phone: (216) 368-2490 Fax: NA
Email: hisashi.fujioka@case.edu
IP 114
Research: Mitochondrial studies in cells of mammalian origin


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Charles Hoppel, M.D.
Professor of Pharmacology
Professor of Medicine
Phone: (216) 368-3147 Fax: (216) 368-3395
Email: charles.hoppel@case.edu
W147 Wood Building
Research: The main focus of the laboratory is mitochondrial fatty acid oxidation.


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Yoshikazu Imanishi, Ph.D.
Assistant Professor
Phone: (216) 368-5226 Fax: (216) 368-1300
Email: yoshikazu.imanishi@case.edu
RT300 Research Tower
Research: Biochemistry of Phototransduction and the Visual Cycle.
Laboratory


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Grace Jin, Ph.D.
Instructor
Phone: (216) 368-2152 Fax: (216) 368-1300
Email: hui.jin@case.edu

Research: Growth hormone signaling in cancer


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Ruth Keri, Ph.D.
Associate Professor
Phone: (216) 368-3495 Fax: (216) 368-3395
Email: ruth.keri@case.edu
RT300 Research Tower
Research: Hormonal control of mammary gland development and construction of transgenic mouse models of breast cancer; functional genomics of mammary gland development and cancer.
Laboratory


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Janos Kerner, Ph.D.
Associate Professor
Phone: (216) 368-5358 Fax:
Email: janos.kerner@case.edu
WG-48
Research: The elucidation of the functions of carnitine acyltransferases and acylcarnitines in intermediary metabolism and the investigation of the regulation of mitochondrial malonyl-CoA sensitive carnitine palmitoyltransferase (CPT-I).


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Paul MacDonald, Ph.D.
Associate Professor
Phone: (216) 368-2466 Fax: (216) 368-3395
Email: paul.macdonald@case.edu
W309 Wood Building
Research: The global objective of my laboratory is to understand the molecular details and signaling mechanisms involved in Vitamin-D Receptor-mediated gene expression.


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Michael Maguire, Ph.D.
Professor
Professor of Molecular Biology and Microbiology
Phone: (216) 368-6187 Fax: (216) 368-3395
Email: michael.maguire@case.edu
W317A Wood Building
Research: Role of Mg2+ and Mn2+ in bacterial pathogenesis. Physiological and biochemical roles of Mg2+; characterization and regulation of plasma membrane Mg2+ and Mn2+ transport systems
Laboratory


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Rachel Mann, Ph.D.
Instructor
Phone: (216) 368-2528 Fax: NA
Email: rachel.mann@case.edu
Wolstein Research Bldg. 2521
Research: The Case Transgenic & Targeting Facility performs pronuclear injection for development of transgenic mice as a service to all members of the Case research community. Rederivation, husbandry training, and cryopreservation are other available services.


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John Mieyal, Ph.D.
Professor, Department Vice Chair
Phone: (216) 368-3383 Fax: (216) 368-3395
Email: john.mieyal@case.edu
RT300 Research Tower
Research: Enzymatic reaction mechanisms involved in intracellular sulfhydryl homeostasis and redox signal transduction in health and diseases, including cancer, cardiovascular and neurological disorders, and diabetes.


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Vera Moiseenkova-Bell, Ph.D.
Assistant Professor
Phone: (216) 368-2641 Fax: (216) 368-1300
Email: vera.moiseenkova-bell@case.edu
W151D Wood Building
Research: Molecular mechanisms and structural basis of pain and temperature sensation (structure-functional analysis of TRP and 2PK channels).


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Monica Montano, Ph.D.
Associate Professor
Phone: (216) 368-3378 Fax: (216) 368-3395
Email: monica.montano@case.edu
W305B Wood Building
Research: My laboratory is involved in the identification and characterization of ER-regulated genes in breast cancer cells.


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Noa Noy, Ph.D.
Professor
Phone: (216) 368-0302 Fax: (216) 368-1300
Email: noa.noy@case.edu
W333 Wood Building
Research: Mechanisms of action and biological functions of nuclear hormone receptors.


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Mariana Rosca, M.D.
Instructor
Phone: (216) 368-4783 Fax: NA
Email: Mariana.rosca@case.edu
SOM W148
Research:


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Shasta Sabo, Ph.D.
Assistant Professor
Phone: (216) 368-5683 Fax: (216) 368-1300
Email: shasta.sabo@case.edu
W343B Wood Building
Research: Our research seeks to understand formation of synapses between CNS neurons.


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Ruth Siegel, Ph.D.
Professor
Director of the Pharmacological Sciences Consortium Core Image Analysis Facility
Phone: (216) 368-5554 Fax: (216) 368-3395
Email: ruth.siegel@case.edu
W309C Wood Building
Research: Our research seeks to understand events that regulate the postnatal differentiation of the rat cerebellum.


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Derek Taylor, Ph.D.
Assistant Professor
Phone: (216) 368-0684 Fax:
Email: derek.taylor@case.edu
W151C Wood Building
Research: Macromolecular structure and function.


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Johannes von Lintig, Ph.D.
Assistant Professor
Phone: (216) 368-3528 Fax: (216) 368-1300
Email: Johannes.vonlintig@case.edu
W333 Wood Building
Research: Retinoids are essential for processes ranging from development to vision, cell proliferation and metabolic control.


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Leslie Webster, M.D.
Professor Emeritus and Consultant
Phone: (216) 368-0850 Fax: (216) 368-1300
Email: leslie.webster@uhhs.com
SOM W431
Research:


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Amy Wilson-Delfosse, Ph.D.
Associate Professor
Assistant Dean for Basic Science Education
Phone: (216) 368-3494 Fax: (216) 368-3395
Email: amy.wilson-delfosse@case.edu
W305C Wood Building
Research: Elucidation of the mechanisms underlying the upstream regulation of Cdc42Hs, a GTPase that plays a critical role in mediating processes associated with cell growth.


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Youwei Zhang, Ph.D.
Assistant Professor
Phone: (216) 368-7588 Fax: (216) 368-1300
Email: youwei.zhang@case.edu
W343A Wood Building
Research: Understanding the molecular mechanisms of DNA damage and replication checkpoint and their potential in cancer therapy
Laboratory