department of pharmacology


Primary Faculty

Krzysztof Palczewski


Krzysztof Palczewski, Ph.D.
Professor and Department Chair
Phone: (216) 368-4497 Fax: (216) 368-1300
Email: kxp65@case.edu
W321 Wood Building
Research: Mapping the Visual Transduction System.
Laboratory


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Chris Dealwis, Ph.D.
Associate Professor
Phone: (216) 368-1652, 368-3337 Fax: (216) 368-1300
Email: chris.dealwis@case.edu
W333
Research: To study the structure-function relationship of macromolecules using structural biology and biochemical tools.


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Andreas Engel, Ph.D.
Professor
Phone: (216) 368-0411 Fax: (216) 368-1300
Email: Andreas.Engel@case.edu
RT300 Research Towers
Research: Research concerns the structure and function of membrane proteins of different origin. A major effort is invested in the study of aquaglyceroporins. Electron crystallography and atomic force microscopy are used to analyze two-dimensional crystals assembled from membrane proteins and lipids


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John Feng, Ph.D.
Mt. Sinai Scholar
Assistant Professor, Department of Pharmacology, School of Medicine
Assistant Professor, Department of Electronic Engineering and Computer Science, School of Engineering
Case Western Reserve University
Phone: (216) 368-3751 Fax: (216) 368-1300
Email: john.feng@case.edu
W309A Wood Building
Research: Dissecting the genetic mechanisms of dopamine neurotransmission-related human diseases
Laboratory


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Marcin Golczak, Ph.D.
Assistant professor
Phone: (216)-368-0040 Fax: (216) 368-1300
Email: mxg149@case.edu
W317
Research: Molecular biology of vision, Retinoid metabolism


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Maria Hatzoglou, Ph.D.
Professor
Phone: 216-368-3012 Fax:
Email: mxh8@case.edu
Wood Reseract Tower (RT-600-8)
Research: Cellular response to stress and development of disease


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Charles Hoppel, M.D.
Professor of Pharmacology and Medicine
Chief of Clinical Pharmacology
Director of the Center for Mitochondrial Diseases
Phone: (216) 368-3147 Fax: 216-368-1300
Email: charles.hoppel@case.edu
W147 Wood Building
Research: The main focus of the laboratory is mitochondrial fatty acid oxidation.


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Yoshikazu Imanishi, Ph.D.
Assistant Professor
Phone: (216) 368-5226 Fax: (216) 368-1300
Email: yoshikazu.imanishi@case.edu
W515 Wood Building
Research: Cell Biology of Photoreceptor Morphogenesis
Laboratory


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Beata Jastrzebska, Ph.D.
Instructor
Phone: (216) 368-0040 Fax: (216) 368-1300
Email: beata.jastrzebska@case.edu
W317
Research: Structural biology of macromolecules


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Ruth Keri, Ph.D.
Professor and Vice Chair
Department of Pharmacology
Associate Director for Basic Research
Case Comprehensive Cancer Center
Phone: (216) 368-3495 Fax: 216-368-1300
Email: ruth.keri@case.edu
RT300 Research Tower
Research: Hormonal control of mammary gland development and construction of transgenic mouse models of breast cancer; functional genomics of mammary gland development and cancer.
Laboratory


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Janos Kerner, Ph.D.
Associate Professor
Phone: (216) 368-5358 Fax: 216-368-1300
Email: janos.kerner@case.edu
W147C
Research: The elucidation of the functions of carnitine acyltransferases and acylcarnitines in intermediary metabolism and the investigation of the regulation of mitochondrial malonyl-CoA sensitive carnitine palmitoyltransferase (CPT-I).


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Philip Kiser, Ph. D.
PharmD, Instructor
Phone: (216) 368-8794 Fax: 216-368-1300
Email: pdk7@case.edu
W317
Research: Retinoid biochemistry, x-ray crystallography, pharmacology


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Paul MacDonald, Ph.D.
Associate Professor
Phone: (216) 368-2466 Fax: 216-368-1300
Email: paul.macdonald@case.edu
W309 Wood Building
Research: The global objective of my laboratory is to understand the molecular details and signaling mechanisms involved in Vitamin-D Receptor-mediated gene expression.


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Michael Maguire, Ph.D.
Professor Emeritus, Pharmacology
Phone: (216) 368-6186 Fax: 216-368-1300
Email: michael.maguire@case.edu
W317A Wood Building
Research: Role of Mg2+ and Mn2+ in bacterial pathogenesis. Physiological and biochemical roles of Mg2+; characterization and regulation of plasma membrane Mg2+ and Mn2+ transport systems
Laboratory


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Jason Mears, Ph.D.
Assistant Professor
Phone: (216) 368-3348 Fax: 216-368-1300
Email: Jam348@case.edu
W147D
Research: Structure and function of eukaryotic proteins that regulate mitochondrial dynamics. Cryo-electron microscopy, biochemical and computational methods


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John Mieyal, Ph.D.
Professor
Department Vice Chair
Director of the MTTP
Phone: (216) 368-3383 Fax: 216-368-1300
Email: john.mieyal@case.edu
RT300 Research Tower
Research: Enzymatic reaction mechanisms involved in intracellular sulfhydryl homeostasis and redox signal transduction in health and diseases, including cancer, cardiovascular and neurological disorders, and diabetes.


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Vera Moiseenkova-Bell, Ph.D.
Assistant Professor
Phone: (216) 368-2641 Fax: (216) 368-1300
Email: vera.moiseenkova-bell@case.edu
W151D Wood Building
Research: Molecular mechanisms and structural basis of pain sensation.
Laboratory


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Monica Montano, Ph.D.
Associate Professor
Phone: (216) 368-3378 Fax: 216-368-1300
Email: monica.montano@case.edu
W305B Wood Building
Research: My laboratory is involved in the identification and characterization of ER-regulated genes in breast cancer cells.


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Marvin Nieman, Ph.D.
Assistant Professor
Phone: (216) 368-0250 Fax: 216-368-1300
Email: nieman@case.edu
School of Medicine W305C
Research: The goal of our research is to identify potential targets for anti-platelet therapies that do not pose a risk for bleeding by understanding how PAR1 and PAR4 interact with one another to mediate thrombin signaling for platelet activation.
Laboratory


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Shasta Sabo, Ph.D.
Assistant Professor
Phone: (216) 368-5683 Fax: (216) 368-1300
Email: shasta.sabo@case.edu
W343B Wood Building
Research: Our research seeks to understand formation of synapses between CNS neurons.
Laboratory


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Ruth Siegel, Ph.D.
Professor
Director of the Pharmacological Sciences Consortium Core Image Analysis Facility
Phone: (216) 368-5554 Fax: 216-368-1300
Email: ruth.siegel@case.edu
W309C Wood Building
Research: Our research seeks to understand events that regulate the postnatal differentiation of the rat cerebellum.


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Phoebe L. Stewart, Ph.D.
Director, Cleveland Center for Membrane and Structural Biology Professor, Department of Pharmacology Case Western Reserve University
Phone: (216) 368-4349 Fax: 216-368-1300
Email: pls47@case.edu
W303
Research: Structure of macromolecular assemblies by cryo-electron microscopy and three-dimensional image processing
Laboratory


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Derek Taylor, Ph.D.
Assistant Professor
Phone: (216) 368-0684 Fax: 216-368-1300
Email: derek.taylor@case.edu
W151C Wood Building
Research: Macromolecular structure and function.
Laboratory


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Johannes von Lintig, Ph.D.
Associate Professor with Tenure, Pharmacology
Phone: (216) 368-3528 Fax: (216) 368-1300
Email: Johannes.vonlintig@case.edu
W341
Research: Retinoids are essential for processes ranging from development to vision, cell proliferation and metabolic control.


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Leslie Webster, M.D.
Professor Emeritus and Consultant
Phone: (216) 368-0850 Fax: (216) 368-1300
Email: leslie.webster@case.edu
SOM W443
Research:


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Amy Wilson-Delfosse, Ph.D.
Professor and Associate Dean of Curriculum
Phone: (216) 368-3494 Fax: 216-368-1300
Email: amy.wilson-delfosse@case.edu
RT300 Wood Research Tower
Research: Elucidation of the mechanisms underlying the upstream regulation of Cdc42Hs, a GTPase that plays a critical role in mediating processes associated with cell growth.


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Youwei Zhang, Ph.D.
Assistant Professor
Phone: (216) 368-7588 Fax: (216) 368-1300
Email: youwei.zhang@case.edu
W343A Wood Building
Research: Understanding the molecular mechanisms of DNA damage and replication checkpoint and their potential in cancer therapy
Laboratory