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Krzysztof Palczewski, Ph.D.

2000 Publications

Cideciyan AV, Haeseleer F, Fariss RN, Aleman TS, Jang GF, Verlinde CL, Marmor MF, Jacobson SG, Palczewski K : Rod and cone visual cycle consequences of a null mutation in the 11-cis-retinol dehydrogenase gene in man. Visual Neurosci 2000;17:667-78.

 

Sokal I, Li N, Verlinde CL, Haeseleer F, Baehr W, Palczewski K : Ca2+-binding proteins in the retina: From discovery to etiology of human disease. Biochim Biophys Acta 2000;1498:233-51.

 

Imamoto Y, Kataoka M, Tokunaga F, Palczewski K : Light-induced conformational changes of rhodopsin probed by fluorescent Alexa594 immobilized on the cytoplasmic surface. Biochemistry 2000;39:15225-33.

 

McBee JK, Kuksa V, Alvarez R, de Lera AR, Prezhdo O, Haeseleer F, Sokal I, Palczewski K : Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins. Biochemistry 2000;39:11370-80.

 

Jang GF, McBee JK, Alekseev AM, Haeseleer F, Palczewski K : Stereoisomeric specificity of the retinoid cycle in the vertebrate retina. J Biol Chem 2000;275:28128-38.

 

Palczewski K , Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M: Crystal structure of rhodopsin: A G-protein-coupled receptor. Science 2000;289:739-45.

 

Van Hooser JP, Aleman TS, He YG, Cideciyan AV, Kuksa V, Pittler SJ, Stone EM, Jacobson SG, Palczewski K : Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness. Proc Natl Acad Sci USA 2000; 97:8623-8.

 

Driessen CA, Winkens HJ, Hoffmann K, Kuhlmann LD, Janssen BP, Van Vugt AH, Van Hooser JP, Wieringa BE, Deutman AF, Palczewski K , Ruether K, Janssen JJ: Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters. Molec Cell Biol 2000;20:4275-87.

 

Mukherjee S, Gurevich VV, Jones JCR, Casanova JE, Frank SR, Maizels ET, Bader MF, Kahn RA, Palczewski K , Aktories K, Hunzicker-Dunn M: The ADP ribosylation factor nucleotide exchange factor ARNO promotes ß-arrestin release necessary to luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci USA 2000;97:5901-6.

 

Okada T, Le Trong I, Fox BA, Behnke CA, Stenkamp RE, Palczewski K : X-ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles. J Struc Biol 2000;130:73-80.

 

Whitten ME, Yokoyama K, Schieltz D, Ghomashchi F, Lam D, Yates JR III, Palczewski K , Gelb MH: Structural analysis of protein prenyl groups and associated C-terminal modifications. Meth Enzymol 2000;316:436-51.

 

Haeseleer F, Palczewski K : Short-chain dehydrogenases/reductases in the retina. Meth Enzymol 2000;316:372-83.

Saari JC, Garwin GG, Haeseleer F, Jang GF, Palczewski K : Phase partition and HPLC assays of retinoid dehydrogenases. Meth Enzymol 2000;316:359-71.

 

Stecher H, Palczewski K : Multienzyme analysis of visual cycle. Meth Enzymol 2000;316:330-344.

Palczewski K , Polans AS, Baehr W, Ames JB: Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseases. Bioessays 2000;22(4):337-50.

 

Haeseleer F, Sokal I, Verlinde CL, Erdjument-Bromage H, Tempst P, Pronin AN, Benovic JL, Fariss RN, Palczewski K : Five members of a novel Ca2+-binding protein (CaBP) subfamily with similarity to calmodulin. J Biol Chem 2000;275:1247-60.