Krzysztof Palczewski, Ph.D.
2005 Publications
Golczak M, Imanishi Y, Kuksa V, Maeda T, Kubota R, and Palczewski K: Lecithin retinol acyl transferase (LRAT) is responsible for amidation of retinylamine, a potent inhibitor of the visual cycle. J. Biol. Chem, 2005, 280: 42263-42272.
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Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, Bennicelli J, Dejneka NS, Pearce-Kelling SE, Maguire AM, Palczewski K, Hauswirth WW, Jacobson SG: Long-term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness. 2005 Molecular Therapies 12: 1072-1082.
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Wingard JN, Chan J, Bosanac I, Haeseleer F, Palczewski K, Ikura M, Ames JB: Structural Analysis of Mg2+ and Ca2+ Binding to Calcium-binding Protein 1 (CaBP1), a Neuron-specific Regulator of Calcium Channels. 2005, J. Biol. Chem. 280: 37461-37470.
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Batten ML, Imanishi Y, Tu DC, Doan T, Zhu L, Pang J, Glushakova L, Moise AR, Baehr W, Van Gelder RN, Hauswirth WW, Rieke F, Palczewski K: Pharmacological and raav gene therapy rescue of visual functions in a blind mouse model of leber congenital amaurosis. 2005 Plos, 2: e333.
Editorial: Tackling Inherited Blindness
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Zhang L, Salom D, He J, Okun A, Ballesteros J, Palczewski K, Li N: Expression of functional G protein-coupled receptors in photoreceptors of transgenic Xenopus laevis . 2005, Biochemistry 44: 14509-14518.
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Maeda T, Lem J, Palczewski K, Haeseleer F: A critical role of CaBP4 in the cone synapse. 2005 Invest Ophthalmol Vis Sci 2005, 46: 4320-4327.
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O'Byrne SM, Wongsiriroj N, Libien JM, Vogel S, Goldberg IJ, Baehr W, Palczewski K , Blaner WS: Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (lrat). J. Biol. Chem. 2005, 280: 35647-35657.
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Bartl FJ, Fritze O, Ritter E, Herrmann R, Kuksa V, Palczewski K, Hofmann KP, and Ernst OP: Partial agonism in a G protein-coupled receptor: role of retinal's ring structure in rhodopsin activation. J. Biol Chem. 2005; 280: 34259-67
Supplement
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Park PS-H, Palczewski K
News and Views: G protein-coupled receptor signaling islands revealed.
Nature Chemical Biology 2005, 1: 184-185.
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Alexander R. Moise, Vladimir Kuksa, William S. Blaner, Wolfgang Baehr, and Krzysztof Palczewski
Metabolism and Transactivation Activity of 13,14-Dihydroretinoic Acid
(see also: Supplement)
J. Biol. Chem. 2005; 280(30): 27815-27825
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Paul S.-H. Park and Krzysztof Palczewski
Diversifying the Repertoire of G Protein-Coupled Receptors Through Oligomerization
PNAS 2005 June 21; 102(25): 8793–8794
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Ronald E. Stenkamp, David C. Teller, and Krzysztof Palczewski
Rhodopsin: A Structural Primer for G Protein-Coupled Receptors
Arch. Pharm. Chem. Life Sci. 2005; 338: 209-216
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Marcin Golczak, Vladimir Kuksa, Tadao Maeda, Alexander R. Moise, and Krzysztof Palczewski
Positively Charged Retinoids are Potent and Selective Inhibitors of the trans-cis Isomerization in the Retinoid (Visual) Cycle
PNAS 2005 June 7; 102(23): 8162-8167
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Akiko Maeda, Tadao Maeda, Yoshikazu Imanishi, Vladimir Kuksa, Andrei Alekseev, J. Darin Bronson, Houbin Zhang, Li Zhu, Wenyu Sun, David A. Saperstein, Fred Rieke, Wolfgang Baehr, and Krzysztof Palczewski
Role of Photoreceptor-specific Retinol Dehydrogenase in the Retinoid Cycle in Vivo
J. Biol. Chem. 2005; 280: 18822-18832.
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Samuel G. Jacobson, Tomas S. Aleman, Artur V. Cideciyan, Alexander Sumaroka, Sharon B. Schwartz, Elizabeth A. M. Windsor, Elias I. Traboulsi, Elise Heon, Steven J. Pittler, Ann H. Milam, Albert M. Maguire, Krzysztof Palczewski, Edwin M. Stone, and Jean Bennett
Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success
PNAS, April 26, 2005, vol. 102, no. 17, 6177–6182
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Alexander R. Moise, Johannes von Lintig and Krzysztof Palczewski
Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids
TRENDS in Plant Science Vol.10 No.4 April 2005
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Izabela Sokal, William J. Dupps, Michael A. Grassi, Jeremiah Brown, Jr, Louisa M. Affatigato, Nirmalya Roychowdhury, Lili Yang, Sławomir Filipek, Krzysztof Palczewski, Edwin M. Stone, and Wolfgang Baehr
A Novel GCAP1 Missense Mutation (L151F) in a Large Family with Autosomal Dominant Cone-Rod Dystrophy (adCORD)
Investigative Ophthalmology & Visual Science, April 2005, Vol. 46, No. 4.
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Kim TS, Maeda A, Maeda T, Heinlein C, Kedishvili N, Palczewski K, Nelson PS.
Delayed dark adaptation in 11-cis-retinol dehydrogenase deficient mice: A role of RDH11 in visual processes in vivo.
J. Biol. Chem., Vol. 280, Issue 10, 8694-8704, March 11, 2005.
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Akiko Maeda, John W. Crabb, and Krzysztof Palczewski
Microsomal Glutathione S-Transferase 1 in the Retinal Pigment Epithelium: Protection against Oxidative Stress and a Potential Role in Aging
Biochemistry 2005, 44: 480-489.
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