Krzysztof Palczewski, Ph.D.
2006 Publications
Maeda A, Maeda T, Imanishi Y, Sun W, Jastrzebska B, Hatala DA, Winkens HJ, Hofmann KP, Janssen JJ, Baehr W, Driessen CA, and Palczewski K: Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. 2006, J. Biol. Chem. 281: 37697-37704.
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Salom S, Le Trong I, Pohl E, Ballesteros JA, Stenkamp RE, Palczewski K, and Lodowski DT: Improvements in G Protein-coupled receptor purification yield light stable rhodopsin crystals. 2006, J. Struct. Biol. 156: 497-504.
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Palczewski K, Hofmann KP, and Baehr W: Rhodopsin - Advances and Perspectives. 2006, Vision Research. 46: 4425-4426
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Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, and Palczewski K: Structure of the Photoactivated State of Rhodopsin. 2006, Proc Natl Acad Sci USA 103: 16123-16128.
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Domínguez M, Álvarez R; Pérez M, Palczewski K, de Lera AR: The Role of the 11-cis-Retinal Ring Methyl Substituents on Visual Pigment Formation. 2006, ChemBioChem 7: 1815-1825.
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Maeda A, Maeda T, Palczewski K: Improvements in rod and cone functions in mouse model of Fundus Albipunctatus after pharmacological treatments with 9-cis-retinal. 2006, Invest Ophthalmol Vis Sci. 47: 4540-4546.
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Maeda A, Maeda T, Golczak M, Imanishi Y, Leahy P, Kubota R, Palczewski K:Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice. 2006, Molecular Pharmacology 70: 1220-1229.
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Howes KA, Baehr W, Palczewski K: The Retinal Insider. Dry AMD: From Theory to Therapy. 2006, Review of Ophthalmology, Sep 67-73.
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Filipek S, Modzelewska A, Palczewski K, Park, PS-H. Arrestin interaction with rhodopsin: conceptual models. 2006, Cell Biochem. Biophys. 46: 1-16.
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Haire SE, Pang J, Boye SL, Sokal I, Craft CM, Palczewski K, Hauswirth WW, Semple-Rowland SL: AAV-GC1 restores function to cone photoreceptors in postnatal GC1 KO mouse retina. 2006, Invest Ophthalmol Vis Sci 47: 3745-3753.
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Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska J, Sun W, Saperstein DA, Palczewski K: Autosomal recessive retinitis pigmentosa: E150K mutation in the opsin gene. 2006, J. Biol. Chem. 281: 22289-22298.
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Williams ML, Coleman JE, Haire SE, Aleman TS, Cideciyan AV, Sokal
I, Palczewski K, Jacobson SG, and Semple-Rowland SL: Lentiviral Expression of Guanylate Cyclase-1 (GC1) in the Retina Restores Vision in an Avian Model of Childhood Blindness. PLOS Medicine, 2006, 3: e201.
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Palczewski K: G Protein-Coupled Receptor Rhodopsin. 2006, Annual Review of Biochemistry, 75: 743-767.
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Tu DC, Anderson L, Owens LA, Golczak M, Doyle SE, McCall M, Redmond TM, Menaker M, Palczewski K, Van Gelder RN: Inner retinal photoreception is independent of the visual retinoid cycle. 2006, Proc. Natl. Acad. Sci. 103: 10426-10431.
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Stephen R, Palczewski K, and Sousa MC: The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP–linked Cone Dystrophies. J. Mol. Biol. 2006, 359: 266-275.
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Jastrzebska B, Fotiadis D, Jang G-F, Stenkamp RE, Engel A, and Palczewski K: Functional and structural characterization of rhodopsin oligomers. J. Biol. Chem. 2006, 281: 11917-11922.
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Fotiadis D, Jastrzebska B, Philippsen A, Müller DJ, Palczewski K, and Engel A: Structure of the Rhodopsin Dimer: A Working Model for G-Protein Coupled Receptors. Current Op. Structural Biol. 2006, 16: 252-259.
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Mansoor SE, Palczewski K, Farrens DL: Rhodopsin self-associates in asolectin liposomes. Proc Natl Acad Sci USA 2006, 103: 3060-3065.
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Sapra KT, Park PS-H, Filipek S, Engel A, Muller DJ, and Palczewski K: Detecting molecular interactions that stabilize native bovine rhodopsin. J. Mol. Biol. 2006, 358: 255-269.
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Maeda A, Maeda T, Imanishi Y, Golczak M, Moise AR, and Palczewski K: Aberrant metabolites in mouse models of congenital blinding diseases: Formation and storage of retinyl esters. Biochemistry 2006, 45: 4210-4219.
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