Krzysztof Palczewski, Ph.D.
1990-1994 Publications
Ohguro H, Palczewski K , Walsh KA, Johnson RS: Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange. Protein Sci 1994;3:2428-34.
Subbaraya I, Ruiz CC, Helekar BS, Zhao X, Gorczyca W, Pettenati MJ, Rao PN, Palczewski K , Baehr W: Molecular characterization of human and mouse photoreceptor guanylate cyclase activating protein (GCAP) and chromosomal localization of the human gene. J Biol Chem 1994;269: 31080-9.
Morrison RS, Hendrickson S, Shi E, Kan M, McKeehan W, Rudnicka-Nawrot M, Palczewski K : Inositolhexakisphosphate (InsP6): an antagonist of fibroblast growth factor receptor binding and activity. In Vitro Cell Dev Biol 1994;30A:783-9.
Palczewski K , Jäger S, Buczylko J, Crouch RK, Bredberg DL, Hofmann KP, Asson-Batres MA, Saari JC: Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction. Biochemistry 1994;33:13741-50.
Palczewski K , Subbaraya I, Gorczyca WA, Helekar BS, Ruiz CC, Ohguro H, Huang J, Zhao X, Crabb JW, Johnson RS, Walsh KA, Gray-Keller MP, Detwiler PB, Baehr W: Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase activating protein. Neuron 1994;13:395-404.
Johnson RS, Ohguro H, Palczewski K , Hurley JB, Walsh KA, Neubert TA: Heterogeneous N-acylation is a tissue- and species-specific posttranslational modification. J Biol Chem 1994;269:21067-71
Robinson PR, Buczylko J, Ohguro H, Palczewski K : Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase. Proc Natl Acad Sci USA 1994;91:5411-15.
Smith WC, Milam AH, Dugger D, Arendt A, Hargrave PA, Palczewski K : A splice variant of arrestin: Molecular cloning and localization in bovine retina. J Biol Chem 1994;269: 15407-10.
Gorczyca W, Van Hooser JP, Palczewski K : Nucleotide inhibitors and activators of retinal guanylyl cyclase. Biochemistry 1994;33:3217-22.
Gorczyca WA, Gray-Keller MP, Detwiler PB, Palczewski K : Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods. Proc Natl Acad Sci USA 1994;91: 4014-18.
Palczewski K , Buczylko J, Ohguro H, Annan RS, Carr SA, Crabb JW, Kaplan MW, Johnson RS, Walsh KA: Characterization of a truncated form of arrestin isolated from bovine rod outer segments. Protein Sci 1994;3:314-24.
Polans AS, Palczewski K , Asson-Batres MA, Ohguro H, Witkowska D, Haley TL, Raizer L, Crabb JW: Purification and primary structure of Capl, an S-100-related calcium-binding protein isolated from bovine retina. J Biol Chem 1994;269:6233-40.
Ohguro H, Johnson RS, Ericksson LH, Walsh KA, Palczewski K : Control of rhodopsin multiple phosphorylation. Biochemistry 1994;33:1023-8.
Pulvermüller A, Palczewski K , Hofmann KP: Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation. Biochemistry 1993;32:14082-8.
Saari JC, Bredberg DL, Garwin GG, Buczylko J, Wheeler T, Palczewski K : Assays of retinoid dehydrogenases by phase partition. Anal Biochem 1993;213:128-32.
Adamus G, Arendt A, Hargrave PA, Heyduk T, Palczewski K : The kinetics of multiphosphorylation of rhodopsin. Arch Biochem Biophys 1993;304:443-7.
Ohguro H, Chiba S, Igarashi Y, Matsumoto H, Akino T, Palczewski K : b-Arrestin and arrestin are recognized by autoantibodies in sera from multiple sclerosis patients. Proc Natl Acad Sci USA 1993;90:3241-5.
Ohguro H, Palczewski K , Ericsson LH, Walsh KA, Johnson RS: Sequential phosphorylation of rhodopsin at multiple sites. Biochemistry 1993;32:5718-29.
Morrison RS, Giordano SD, Yamaguchi F, Hendrickson S, Berger MS, Palczewski K : Basic fibroblast growth factor expression is required for clonogenic growth of human glioma cells. J Neurosci Res 1993;34:502-9.
Gray-Keller MP, Polans AS, Palczewski K , Detwiler PB: The effect of recoverin-like calcium-binding proteins on the photoresponse of retinal rods. Neuron 1993;10:523-31.
Palczewski K , Buczylko J, Crabb JW, Polans AS: Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin. J Biol Chem 1993; 268:6004-13.
Polans AS, Burton MD, Haley TL, Crabb JW, Palczewski K : Recoverin, but not visinin, is an autoantigen in the human retina identified with a cancer-associated retinopathy. Invest Ophthalmol Vis Sci 1993;34:81-90.
Palczewski K , Buczylko J, Van Hooser P, Carr SA, Huddleston MJ, Crabb JW: Identification of the autophosphorylation sites in rhodopsin kinase. J Biol Chem 1992; 267: 18991-8.
Hofmann KP, Pulvermüller A, Buczylko J, Van Hooser P, Palczewski K : The role of arrestin in regeneration pathway of rhodopsin J Biol Chem 1992;267:15701-6.
Palczewski K , Riazance-Lawrence, JH, Johnson C: Structural properties of arrestin studied by chemical modification and circular dichroism. Biochemistry 1992;31: 3902-6.
Palczewski K , Rispoli G, Detwiler P: The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction. Neuron 1992;3:117-26.
Palczewski K , Pulvermüller A, Buczylko J, Gutmann C, Hofmann KP: Binding of inositol phosphates to arrestin. FEBS Letters 1991;295:195-9.
Lorentz W, Inglese J, Palczewski K , Onorato JJ, Caron MG, Lefkowitz RJ: The receptor kinase family: Primary structure of rhodopsin kinase reveals similarities to the b-adrenergic receptor kinase. Proc Natl Acad Sci USA 1991;88:8715-19.
Palczewski K , Pulvermüller A, Buczylko J, Hofmann KP: Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin. J Biol Chem 1991;266:18649-54.
Palczewski K , Buczylko J, Imami NR, McDowell JH, Hargrave PA: Role of the C-terminal region of arrestin in light-dependent binding to rhodopsin. J Biol Chem 1991;266:15334-9.
Palczewski K , Buczylko J, Kaplan MW, Polans AS, Crabb J: Mechanism of rhodopsin kinase activation. J Biol Chem 1991;266:12949-55.
Palczewski K , Farber DB, Hargrave PA: Elevated level of protein phosphatase 2A activity in retinas of rd mice. Exp Eye Res 1991;53:101-5.
Onorato JJ, Palczewski K , Regan JW, Caron MG, Lefkowitz RJ, Benovic JL: Role of acidic amino acid in peptide substrates of the b-adrenergic receptor kinase and rhodopsin kinase. Biochemistry 1991;30:5118-25.
Polans AS, Buczylko J, Crabb J, Palczewski K : A photoreceptor calcium-binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy. J Cell Biol 1991; 112:981-9.
Ragazzi E, Shryock J, Palczewski K : Properties of solubilized and reconstituted A1 adenosine receptors from bovine brain. Pharmacol Res 1990;24:15-23.
Buczylko J, Gutmann C, Palczewski K : Regulation of rhodopsin kinase by autophosphorylation. Proc Natl Acad Sci USA 1990;88:2568-72.
Palczewski K , Hargrave PA: Studies of ligand binding to arrestin. J Biol Chem 1990;266:4201-6.
Adamus G, Arendt A, Zam ZS, Palczewski K , McDowell JH, Hargrave PA: Anti-rhodopsin monoclonal antibodies of defined specificity, characterization and application. Vision Res 1990;31:17-31.
Fukada Y, Kokame K, Okano T, Shichida Y, Yoshizawa T, McDowell JH, Hargrave PA, Palczewski K : Phosphorylation of iodopsin, chicken red-sensitive cone visual pigment. Biochemistry 1990;29:10102-6.
Palczewski K , Kahn N, Hargrave PA: Nucleoside inhibitors of rhodopsin kinase. Biochemistry 1990;29:6276-82.
Palczewski K , Carruth ME, Adamus G, McDowell JH, Hargrave PA: Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland. Vision Res 1990; 30:1129-37.
Litchfield D, Arendt A, Lozeman FJ, Krebs EG, Hargrave PA, Palczewski K : Synthetic phosphopeptides are substrates for casein kinase II. FEBS Letters 1990;261: 117-20.
Lebioda L, Hargrave PA, Palczewski K : X-ray crystal structure of sangivamycin, a potent inhibitor of protein kinases. FEBS Letters 1990;266;102-4.