department of pharmacology

Krzysztof Palczewski, Ph.D.

2004 Publications

Kitaru Suda, Slawomir Filipek, Krzysztof Palczewski, Andreas Engel and Dimitrios Fotiadis
The supramolecular structure of the GPCR rhodopsin in solution
and native disc membranes

Molecular Membrane Biology; 2004; 21; 435-446.

--------------------------------------------------------------------------------

Park, P. S.-H.; Filipek, S.; Wells, J. W.; Palczewski, K.;
Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future
Biochemistry; 2004; 43(50); 15643-15656.

Video

--------------------------------------------------------------------------------

Beata Jastrzebska, Tadao Maeda, Li Zhu, Dimitrios Fotiadis, Slawomir Filipek, Andreas Engel, Ronald E. Stenkamp, and Krzysztof Palczewski
Functional Characterization of Rhodopsin Monomers and Dimers in Detergents
J. Biol. Chem. 2004 279: 54663–54675.

Supplement

--------------------------------------------------------------------------------

Li Zhu, Geeng-Fu Jang, Beata Jastrzebska, Slawomir Filipek, Susan E. Pearce-Kelling, Gustavo D. Aguirre, Ronald E. Stenkamp, Gregory M. Acland, and Krzysztof Palczewski
A Naturally Occurring Mutation of the Opsin Gene (T4R)
in Dogs Affects Glycosylation and Stability of the G Protein-coupled Receptor

J. Biol. Chem. 2004 279: 53828-53839.

--------------------------------------------------------------------------------

Biological Chemistry

Alexander R. Moise, Vladimir Kuksa, Yoshikazu Imanishi, and Krzysztof Palczewski
Identification of All-trans-Retinol:All-trans-13,14-dihydroretinol Saturase
J. Biol. Chem. 2004 279: 50230–50242.

--------------------------------------------------------------------------------

Yan Liang, Dimitrios Fotiadis, Tadao Maeda, Akiko Maeda, Anna Modzelewska, Slawomir Filipek, David A. Saperstein, Andreas Engel, and Krzysztof Palczewski
Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice
J. Biol. Chem. 2004 279: 48189-48196.

Supplement

--------------------------------------------------------------------------------

Koji M. Nishiguchi, Izabela Sokal, Lili Yang, Nirmalya Roychowdhury, Krzysztof Palczewski, Eliot L. Berson, Thaddeus P. Dryja, and Wolfgang Baehr
A Novel Mutation (I143NT) in Guanylate
Cyclase-Activating Protein 1 (GCAP1) Associated with Autosomal Dominant Cone Degeneration

Invest. Ophthalmol. Vis. Sci. 45: 3863-3870.

--------------------------------------------------------------------------------

Yoshikazu Imanishi, Lili Yang, Izabela Sokal, Slawomir Filipek, Krzysztof Palczewski, Wolfgang Baehr
Diversity of Guanylate Cyclase-Activating
Proteins (GCAPs) in Teleost Fish: Characterization of Three Novel GCAPs (GCAP4, GCAP5, GCAP7) from Zebrafish (Danio rerio) and Prediction of Eight GCAPs (GCAP1-8) in Pufferfish (Fugu rubripes)

J Mol Evol (2004) 59:204–217

--------------------------------------------------------------------------------

Tu, Daniel C., Batten, Matthew L., Palczewski, Krzysztof, Van Gelder, Russell N.
Nonvisual Photoreception in the Chick Iris
Science 2004 306: 129-131

Supplementary Methods

Supplementary Video 1

Supplementary Video 2

--------------------------------------------------------------------------------

 

Françoise Haeseleer, Yoshikazu Imanishi, Tadao Maeda, Daniel E Possin, Akiko Maeda, Amy Lee, Fred Rieke & Krzysztof Palczewski
Essential role of Ca2+-binding protein 4,
a Cav1.4 channel regulator, in photoreceptor synaptic function

Nature Neuroscience 7, 1079 - 1087 (2004).

Featured on the Nature Neuroscience Website!

 

--------------------------------------------------------------------------------

Lalita Subramanian, John W. Crabb, Jos Cox, Isabelle Durussel, Teresa M. Walker, Paul R. van Ginkel, Saswati Bhattacharya, Julia M. Dellaria, Krzysztof Palczewski, and Arthur S. Polans
Ca2+ Binding to EF Hands 1 and 3 Is Essential for the Interaction of Apoptosis-Linked Gene-2 with Alix/AIP1 in Ocular Melanoma
Biochemistry, 43 (35), 11175 -11186, 2004.
--------------------------------------------------------------------------------

Alex Mamman, Jeanette P. Simpson, Alan Nighorn, Yoshikazu Imanishi, Krzysztof Palczewski, Gabriele V. Ronnett and Cheil Moon
Hippocalcin in the olfactory epithelium: a mediator of second messenger signaling
Biochemical and Biophysical Research Communications, Volume 322, Issue 4, 1 October 2004, Pages 1131-1139.
--------------------------------------------------------------------------------

Krzysztof Palczewski, Izabela Sokal and Wolfgang Baehr
Guanylate cyclase-activating proteins: structure, function, and diversity
Biochemical and Biophysical Research Communications, Volume 322, Issue 4, 1 October 2004, Pages 1123-1130.
--------------------------------------------------------------------------------

Yoshikazu Imanishi, Volker Gerke, and Krzysztof Palczewski
Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies
J. Cell Biol. 2004 166: 447-453.
--------------------------------------------------------------------------------

 

Filipek S, Krzysko KA, Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K.
A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface.
Photochem Photobiol Sci. 2004 Jun;3(6):628-38. Epub 2004 Feb 27.

 

--------------------------------------------------------

Dimitrios Fotiadis, Yan Liang, Slawomir Filipek, David A. Saperstein, Andreas Engel and Krzysztof Palczewski
The G protein-coupled receptor rhodopsin in the native membrane
FEBS Letters, Volume 564, Issue 3, pp. 281-288
--------------------------------------------------------------------------------

Aleman TS, Jacobson SG, Chico JD, Scott ML, Cheung AY, Windsor EA, Furushima M, Redmond TM, Bennett J, Palczewski K, Cideciyan AV.
Impairment of the Transient Pupillary Light Reflex in Rpe65(-/-) Mice and Humans with Leber Congenital Amaurosis.
Invest Ophthalmol Vis Sci. 2004 Apr;45(4):1259-1271.
--------------------------------------------------------------------------------

Matthew L. Batten, Yoshikazu Imanishi, Tadao Maeda, Daniel C. Tu, Alexander R. Moise, Darin Bronson, Daniel Possin, Russell N. Van Gelder, Wolfgang Baehr, and Krzysztof Palczewski
Lecithin-retinol Acyltransferase Is Essential for Accumulation of All-trans-Retinyl Esters in the Eye and in the Liver
J. Biol. Chem. 2004 279: 10422-10432.
--------------------------------------------------------------------------------

Yoshikazu Imanishi, Matthew L. Batten, David W. Piston, Wolfgang Baehr, and Krzysztof Palczewski
Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye
J. Cell Biol., Feb 2004; 164: 373 - 383.

See also:
Alan W. Dove
New structure found in plain sight
J. Cell Biol., Feb 2004; 164: 332.